Yale University

The diagnostic performance of a single GeneXpert MTB/RIF assay in an intensified tuberculosis case finding survey among HIV-infected prisoners in Malaysia.

TitleThe diagnostic performance of a single GeneXpert MTB/RIF assay in an intensified tuberculosis case finding survey among HIV-infected prisoners in Malaysia.
Publication TypeJournal Article
Year of Publication2013
AuthorsAl-Darraji, Haider Abdulrazzaq Abed, Humaira Abd Razak, Kee Peng Ng, Frederick L. Altice, and Adeeba Kamarulzaman
JournalPloS one
Volume8
Issue9
Paginatione73717
Date Published2013
ISSN1932-6203
KeywordsAdult, Bacteriological Techniques, Diagnostic Tests, Routine, Female, HIV Infections, Humans, Malaysia, Male, Multivariate Analysis, Mycobacterium tuberculosis, Prisoners, Reproducibility of Results, Sensitivity and Specificity, Sputum, Tuberculosis, Pulmonary
AbstractDelays in tuberculosis (TB) diagnosis, particularly in prisons, is associated with detrimental outcomes. The new GeneXpert MTB/RIF assay (Xpert) offers accurate and rapid diagnosis of active TB, but its performance in improving case detection in high-transmission congregate settings has yet to be evaluated. We assessed the diagnostic accuracy of a single Xpert assay in an intensified case finding survey among HIV-infected prisoners in Malaysia.
DOI10.1371/journal.pone.0073717
Alternate JournalPLoS ONE

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