Yale University

Effectiveness of first-line antiretroviral therapy and correlates of longitudinal changes in CD4 and viral load among HIV-infected children in Ghana.

TitleEffectiveness of first-line antiretroviral therapy and correlates of longitudinal changes in CD4 and viral load among HIV-infected children in Ghana.
Publication TypeJournal Article
Year of Publication2013
AuthorsBarry, Oliver, Jonathan Powell, Lorna Renner, Evelyn Y. Bonney, Meghan Prin, William Ampofo, Jonas Kusah, Bamenla Goka, Kwamena W. C. Sagoe, Veronika Shabanova, and Elijah Paintsil
JournalBMC infectious diseases
Volume13
Pagination476
Date Published2013
ISSN1471-2334
KeywordsAdolescent, Anti-HIV Agents, CD4-Positive T-Lymphocytes, Child, Child, Preschool, Drug Resistance, Viral, Female, Ghana, HIV Infections, HIV-1, Humans, Infant, Longitudinal Studies, Male, Prospective Studies, Treatment Outcome, Viral Load
AbstractAntiretroviral therapy (ART) scale-up in resource-limited countries, with limited capacity for CD4 and HIV viral load monitoring, presents a unique challenge. We determined the effectiveness of first-line ART in a real world pediatric HIV clinic and explored associations between readily obtainable patient data and the trajectories of change in CD4 count and HIV viral load.
DOI10.1186/1471-2334-13-476
Alternate JournalBMC Infect. Dis.

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