@article {4299, title = {The Validity of Self-Reported Medication Adherence as an Outcome in Clinical Trials of Adherence-Promotion Interventions: Findings from the MACH14 Study.}, journal = {AIDS and behavior}, year = {2014}, month = {2014 Oct 4}, abstract = {In medication adherence-promotion trials, participants in the intervention arm are often cognizant of the researcher{\textquoteright}s aim to improve adherence; this may lead to their inflating reports of their own adherence compared to control arm participants. Using data from 1,247 HIV-positive participants across eight U.S. Studies in the Multi-site Adherence Collaboration on HIV (MACH14) collaboration, we evaluated the validity of self-reported adherence by examining whether its association with two more objective outcomes [1], electronically monitored adherence and [2] viral load, varied by study arm. After adjusting for potential confounders, there was no evidence of greater overestimation of self-reported adherence among intervention arm participants, supporting its potential as a trial outcome indicator.}, issn = {1573-3254}, doi = {10.1007/s10461-014-0905-x}, author = {Simoni, Jane M and Huh, David and Wang, Yan and Wilson, Ira B and Reynolds, Nancy R and Remien, Robert H and Goggin, Kathy and Gross, Robert and Rosen, Marc I and Schneiderman, Neil and Arnsten, Julia and Golin, Carol E and Erlen, Judith A and Bangsberg, David R and Liu, Hong Hu} }