%0 Journal Article %J Lancet %D 2004 %T Predictors of trend in CD4-positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three antiretroviral-drug classes. %A Ledergerber, Bruno %A Lundgren, Jens D %A Walker, A Sarah %A Sabin, Caroline %A Justice, Amy %A Reiss, Peter %A Mussini, Cristina %A Wit, Ferdinand %A d'Arminio Monforte, Antonella %A Weber, Rainer %A Fusco, Gregory %A Staszewski, Schlomo %A Law, Matthew %A Hogg, Robert %A Lampe, Fiona %A Gill, M John %A Castelli, Francesco %A Phillips, Andrew N %K Adult %K Anti-Retroviral Agents %K CD4 Lymphocyte Count %K Cohort Studies %K Female %K Follow-Up Studies %K HIV Infections %K HIV Protease Inhibitors %K HIV-1 %K Humans %K Male %K Middle Aged %K Proportional Hazards Models %K Reverse Transcriptase Inhibitors %K Risk Factors %K Treatment Failure %K Viral Load %N 9428 %P 51-62 %V 364 %X Treatment strategies for patients in whom HIV replication is not suppressed after exposure to several drug classes remain unclear. We aimed to assess the inter-relations between viral load, CD4-cell count, and clinical outcome in patients who had experienced three-class virological failure. %8 2004 Jul 3-9