%0 Journal Article %J Journal of human lactation : official journal of International Lactation Consultant Association %D 2010 %T HIV-negative status is associated with very early onset of lactation among Ghanaian women. %A Otoo, Gloria E %A Marquis, Grace S %A Sellen, Daniel W %A Chapman, Donna J %A PĂ©rez-Escamilla, Rafael %K Adult %K Breast Feeding %K Cohort Studies %K Female %K Ghana %K HIV Seronegativity %K Humans %K Infant %K Infant, Newborn %K Lactation %K Logistic Models %K Longitudinal Studies %K Male %K Mothers %K Perception %K Time Factors %K Time Perception %K Weight Gain %N 2 %P 107-17 %R 10.1007/s10461-009-9532-3 %V 26 %X This is a longitudinal cohort study investigating the association between maternal HIV status and the reported onset of lactation. The Research to Improve Infant Nutrition and Growth project recruited 442 mothers from 3 antenatal clinics in the eastern region of Ghana, based on positive, negative, and unknown HIV status. Onset of lactation was assessed by maternal perception and validated with 2 subsamples: measurement of infant breast milk intake (n = 40) and daily infant weight measurement for 2 weeks (n = 150). Multivariate logistic regression was used to identify predictors of very early onset of lactation (onset of lactation < 6 hours). Predictors of very early onset of lactation include HIV-negative status (odds ratio = 2.68; P = .014), multiparity (odds ratio = 2.93; P = .009), vaginal delivery (odds ratio = 2.55; P = .035), and having a male child (odds ratio = 1.86; P = .032). The findings indicate an association between maternal HIV status and very early onset of lactation. %8 2010 May