Yale University

HIV-1 transmission in injection paraphernalia: heating drug solutions may inactivate HIV-1.

TitleHIV-1 transmission in injection paraphernalia: heating drug solutions may inactivate HIV-1.
Publication TypeJournal Article
Year of Publication1999
AuthorsClatts, M. C., R. Heimer, N. Abdala, L. A. Goldsamt, J. L. Sotheran, K. T. Anderson, T. M. Gallo, L. D. Hoffer, P. A. Luciano, and T. Kyriakides
JournalJournal of acquired immune deficiency syndromes (1999)
Volume22
Issue2
Pagination194-9
Date Published1999 Oct 1
ISSN1525-4135
KeywordsCooking, Equipment Contamination, HIV Infections, HIV-1, Hot Temperature, Humans, Solutions, Substance Abuse, Intravenous, Syringes
AbstractIn response to recent concerns about risk of HIV-1 transmission from drug injection paraphernalia such as cookers, ethnographic methods were used to develop a descriptive typology of the paraphernalia and practices used to prepare and inject illegal drugs. Observational data were then applied in laboratory studies in which a quantitative HIV-1 microculture assay was used to measure the recovery of infectious HIV-1 in cookers. HIV-1 survival inside cookers was a function of the temperature achieved during preparation of drug solutions; HIV-1 was inactivated once temperature exceeded, on average, 65 degrees C. Although different types of cookers, volumes, and heat sources affected survival times, heating cookers 15 seconds or longer reduced viable HIV-1 below detectable levels.
DOI10.1111/j.1360-0443.2010.03149.x
Alternate JournalJ. Acquir. Immune Defic. Syndr.

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