Yale University

HIV coinfection in multidrug- and extensively drug-resistant tuberculosis results in high early mortality.

TitleHIV coinfection in multidrug- and extensively drug-resistant tuberculosis results in high early mortality.
Publication TypeJournal Article
Year of Publication2010
AuthorsGandhi, Neel R., Sarita N. Shah, Jason R. Andrews, Venanzio Vella, Anthony P. Moll, Michelle Scott, Darren Weissman, Claudio Marra, Umesh G. Lalloo, and Gerald H. Friedland
Corporate AuthorsTugela Ferry Care and Research(TF CARES) Collaboration
JournalAmerican journal of respiratory and critical care medicine
Volume181
Issue1
Pagination80-6
Date Published2010 Jan 1
ISSN1535-4970
KeywordsAdult, Extensively Drug-Resistant Tuberculosis, Female, HIV Infections, Humans, Kaplan-Meier Estimate, Male, South Africa
AbstractThe multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) epidemics are rapidly expanding in South Africa. Our initial report of HIV-associated XDR TB in South Africa revealed rapid and near complete mortality. Lower mortality has been described in the literature, but few of these patients have been HIV coinfected.
DOI10.1164/rccm.200907-0989OC
Alternate JournalAm. J. Respir. Crit. Care Med.

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