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Mortality in patients with HIV-1 infection starting antiretroviral therapy in South Africa, Europe, or North America: a collaborative analysis of prospective studies.

TitleMortality in patients with HIV-1 infection starting antiretroviral therapy in South Africa, Europe, or North America: a collaborative analysis of prospective studies.
Publication TypeJournal Article
Year of Publication2014
AuthorsBoulle, Andrew, Michael Schomaker, Margaret T. May, Robert S. Hogg, Bryan E. Shepherd, Susana Monge, Olivia Keiser, Fiona C. Lampe, Janet Giddy, James Ndirangu, Daniela Garone, Matthew Fox, Suzanne M. Ingle, Peter Reiss, Francois Dabis, Dominique Costagliola, Antonella Castagna, Kathrin Ehren, Colin Campbell, John M. Gill, Michael Saag, Amy C. Justice, Jodie Guest, Heidi M. Crane, Matthias Egger, and Jonathan A. C. Sterne
JournalPLoS medicine
Volume11
Issue9
Paginatione1001718
Date Published2014 Sep
ISSN1549-1676
KeywordsAdult, Anti-HIV Agents, Antiretroviral Therapy, Highly Active, Cohort Studies, Cooperative Behavior, Europe, Female, Follow-Up Studies, HIV Infections, HIV-1, Humans, Male, Middle Aged, Mortality, North America, Prospective Studies, South Africa
AbstractHigh early mortality in patients with HIV-1 starting antiretroviral therapy (ART) in sub-Saharan Africa, compared to Europe and North America, is well documented. Longer-term comparisons between settings have been limited by poor ascertainment of mortality in high burden African settings. This study aimed to compare mortality up to four years on ART between South Africa, Europe, and North America.
DOI10.1371/journal.pmed.1001718
Alternate JournalPLoS Med.

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