Yale University

The potential impact of a moderately effective HIV vaccine with rapidly waning protection in South Africa and Thailand.

TitleThe potential impact of a moderately effective HIV vaccine with rapidly waning protection in South Africa and Thailand.
Publication TypeJournal Article
Year of Publication2011
AuthorsAndersson, Kyeen M., and John Stover
JournalVaccine
Volume29
Issue36
Pagination6092-9
Date Published2011 Aug 18
ISSN1873-2518
KeywordsAdolescent, Adult, AIDS Vaccines, Clinical Trials as Topic, Computer Simulation, Female, HIV, HIV Infections, Humans, Immunization Programs, Male, Middle Aged, Models, Theoretical, Sex Workers, South Africa, Thailand, Time Factors, Treatment Outcome, Vaccination, Young Adult
AbstractAlthough published data from the recent ALVAC/AIDSVAX trial in Thailand (RV144) indicated the HIV vaccine provided very modest protection overall (31.2%), new analysis of trial data has suggested higher efficacy levels earlier in the follow-up period. CDC and UNAIDS organized several modeling research teams to explore the implications of the trial results and potential utility of this vaccine.
DOI10.1097/QAI.0b013e3181fbc94f
Alternate JournalVaccine

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