| Title | Predictors of trend in CD4-positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three antiretroviral-drug classes. |
| Publication Type | Journal Article |
| Year of Publication | 2004 |
| Authors | Ledergerber, Bruno, Jens D. Lundgren, Sarah A. Walker, Caroline Sabin, Amy Justice, Peter Reiss, Cristina Mussini, Ferdinand Wit, Antonella d'Arminio Monforte, Rainer Weber, Gregory Fusco, Schlomo Staszewski, Matthew Law, Robert Hogg, Fiona Lampe, John M. Gill, Francesco Castelli, and Andrew N. Phillips |
| Corporate Authors | PLATO Collaboration |
| Journal | Lancet |
| Volume | 364 |
| Issue | 9428 |
| Pagination | 51-62 |
| Date Published | 2004 Jul 3-9 |
| ISSN | 1474-547X |
| Keywords | Adult, Anti-Retroviral Agents, CD4 Lymphocyte Count, Cohort Studies, Female, Follow-Up Studies, HIV Infections, HIV Protease Inhibitors, HIV-1, Humans, Male, Middle Aged, Proportional Hazards Models, Reverse Transcriptase Inhibitors, Risk Factors, Treatment Failure, Viral Load |
| Abstract | Treatment strategies for patients in whom HIV replication is not suppressed after exposure to several drug classes remain unclear. We aimed to assess the inter-relations between viral load, CD4-cell count, and clinical outcome in patients who had experienced three-class virological failure. |
| Alternate Journal | Lancet |
