@article {1013,
	title = {Characteristics of HIV-1-associated Kaposi{\textquoteright}s sarcoma among women and men in South Africa.},
	journal = {International journal of STD \& AIDS},
	volume = {19},
	year = {2008},
	month = {2008 Jun},
	pages = {400-5},
	abstract = {Despite the increase of HIV-1-associated Kaposi{\textquoteright}s sarcoma (KS), little is known about HIV-associated KS in the African setting, particularly among women. A descriptive study of the demographic, clinical, immunological and virological features of AIDS-associated KS from KwaZulu-Natal, South Africa was undertaken. Consecutively, recruited patients were clinically staged; CD4/CD8 cell counts, HIV-1 viral loads and clinical parameters were evaluated. Of the 152 patients (77 male and 75 female) 99\% were black. Females were significantly younger (P = 0.02) and had poorer disease prognosis (odds ratio [OR] = 2.7, 95\% confidence interval [CI] = 1.4-5.4, P = 0.003) and were more likely to have extensive cutaneous KS when compared with males (OR = 3.1, 95\% CI = 1.4-6.7, P = 0.003). One-third of patients had coexisting HIV-related disease, most commonly tuberculosis, and these were more frequent in females (56.7 vs. 43.3\%). In conclusion, HIV-associated KS in South Africans has an equal female-to-male ratio. Females are younger and have more severe disease than males.},
	keywords = {Adult, AIDS-Related Opportunistic Infections, CD4 Lymphocyte Count, Cross-Sectional Studies, Female, HIV Infections, HIV Seropositivity, HIV-1, Humans, Male, Sarcoma, Kaposi, South Africa},
	issn = {0956-4624},
	doi = {10.1258/ijsa.2008.007301},
	author = {Mosam, A and Hurkchand, H P and Cassol, E and Page, T and Cassol, S and Bodasing, U and Aboobaker, J and Dawood, H and Friedland, G H and Coovadia, H M}
}
