@article {1038,
	title = {Sexual risk behaviour of the first cohort undergoing screening for enrollment into Phase I/II HIV vaccine trials in South Africa.},
	journal = {International journal of STD \& AIDS},
	volume = {20},
	year = {2009},
	month = {2009 Feb},
	pages = {95-101},
	abstract = {We assessed risk behaviour in a heterosexual cohort undergoing prescreening for the first Phase I/II HIV vaccine trials in Soweto. We developed a survey and collected self-reported data from HIV-negative potential volunteers. Of 488 participants, most were single and approximately half were from households with incomes below the poverty level. Males reported higher rates of heavy alcohol use (P < 0.001), marijuana use (P < 0.001) and other recreational drug use (P < 0.01). Males reported more sex partners than females in the previous six months (P < 0.001), as well as more casual/anonymous partners (P < 0.001) and one-night stands (P < 0.001). Multivariate analyses revealed substance use and male gender predicted higher risk behaviours, including <100\% condom use with known/suspected HIV-positive partners, having casual/anonymous partners and having more than two partners. For this population, male volunteers may need increased risk-reduction counselling during Phase I/II trials and additional recruitment methods may be necessary to identify high-risk female volunteers for Phase III efficacy trials.},
	keywords = {Adolescent, Adult, AIDS Vaccines, Clinical Trials, Phase I as Topic, Clinical Trials, Phase II as Topic, Cohort Studies, Female, Heterosexuality, HIV Infections, Humans, Male, Middle Aged, Patient Selection, Risk-Taking, Sexual Behavior, South Africa, Young Adult},
	issn = {0956-4624},
	doi = {10.1258/ijsa.2008.008207},
	author = {Andersson, K M and Van Niekerk, R M and Niccolai, L M and Mlungwana, O N and Holdsworth, I M and Bogoshi, M and McIntyre, J A and Gray, G E and Vardas, E}
}
