@article {1059,
	title = {Narrative review: buprenorphine for opioid-dependent patients in office practice.},
	journal = {Annals of internal medicine},
	volume = {148},
	year = {2008},
	month = {2008 May 6},
	pages = {662-70},
	abstract = {The profile of opioid dependence in the United States is changing. Abuse of prescription opioids is more common than that of illicit opioids: Recent data indicate that approximately 1.6 million persons abuse or are dependent on prescription opioids, whereas 323,000 abuse or are dependent on heroin. Despite this prevalence, nearly 80\% of opioid-dependent persons remain untreated. One option for expanding treatment is the use of buprenorphine and the buprenorphine-naloxone combination. Buprenorphine is a partial opioid agonist that can be prescribed by trained physicians and dispensed at pharmacies. This article addresses the clinical presentation of a patient with opioid dependence and describes the relatively new practice of office-based treatment with buprenorphine-naloxone. The different components of treatment; the role of the physician who provides this treatment; and the logistics of treating this growing, multifaceted patient population are also examined.},
	keywords = {Adult, Buprenorphine, Drug Combinations, Female, Humans, Methadone, Naloxone, Narcotic Antagonists, Narcotics, Opioid-Related Disorders, Patient Care Planning, Physician{\textquoteright}s Role, Primary Health Care},
	issn = {1539-3704},
	doi = {10.1002/hpm.1029},
	author = {Sullivan, Lynn E and Fiellin, David A}
}
