@article {1619,
	title = {The practice of office-based buprenorphine treatment of opioid dependence: is it associated with new patients entering into treatment?},
	journal = {Drug and alcohol dependence},
	volume = {79},
	year = {2005},
	month = {2005 Jul},
	pages = {113-6},
	abstract = {Office-based buprenorphine holds the promise of bringing patients who have never received pharmacotherapy into treatment. In a cross-sectional and longitudinal analysis, we compared patients entering a clinical trial of buprenorphine in a Primary Care Clinic (PCC) and those entering a local Opioid Treatment Program (OTP) and we compared the clinical characteristics and treatment outcomes of PCC patients with no history of methadone treatment (new-to-treatment) to those with prior methadone treatment. PCC subjects (N=96) were enrolled in a 26-week randomized clinical trial of office-based buprenorphine/naloxone provided in a PCC. OTP subjects (N=94) were enrolled in methadone maintenance during the same time period. PCC subjects compared with OTP subjects were more likely to be male (77\% versus 55\%, p<0.01), full-time employed (46\% versus 15\%, p<0.001), have no history of methadone treatment (46\% versus 61\%, p<0.05), have fewer years of opioid dependence (10 versus 15, p<0.001), and lower rates of injection drug use (IDU) (44\% versus 60\%, p=0.03). The new-to-treatment PCC subjects were younger (36 years versus 41 years, p=0.001), more likely to be white (77\% versus 57\%, p=0.04), had fewer years of opioid dependence (7 versus 14, p<0.001), were less likely to have a history of IDU (35\% versus 54\%, p=0.07), and had lower rates of hepatitis C (25\% versus 61\%, p=0.002) than subjects with prior methadone treatment. Abstinence and treatment retention were comparable in both groups. The results suggest that office-based treatment of opioid dependence is associated with new types of patients entering into treatment. Treatment outcomes with buprenorphine in a PCC do not vary based on history of prior methadone treatment.},
	keywords = {Adolescent, Adult, Aged, Buprenorphine, Cross-Sectional Studies, Female, Humans, Male, Mental Health Services, Middle Aged, Narcotic Antagonists, Office Visits, Opioid-Related Disorders, Physician{\textquoteright}s Practice Patterns},
	issn = {0376-8716},
	doi = {10.1111/j.1475-6773.2011.01335.x},
	author = {Sullivan, Lynn E and Chawarski, Marek and O{\textquoteright}Connor, Patrick G and Schottenfeld, Richard S and Fiellin, David A}
}
