@article {1625,
	title = {Treatment of heroin dependence with buprenorphine in primary care.},
	journal = {The American journal of drug and alcohol abuse},
	volume = {28},
	year = {2002},
	month = {2002},
	pages = {231-41},
	abstract = {Buprenorphine is an effective treatment for heroin dependence. The feasibility and potential efficacy of buprenorphine with brief counseling in primary care is unknown. We enrolled 14 heroin dependent patients in a 13-week clinical trial using thrice weekly buprenorphine along with brief counseling in the primary care center of an urban medical center. Primary outcomes included urine toxicology and treatment retention. Opioid-positive urine toxicology tests reduced over the 13-week period from 95 to 25\% (p < 0.05). Eleven patients (79\%) had greater than or equal to one week of opioid-free urine toxicologies. Nine patients (64\%) had greater than or equal to three weeks of opioid-free urine toxicologies. Eleven patients (79\%) were retained through the maintenance phase. We conclude that buprenorphine maintenance is feasible in a primary care setting.},
	keywords = {Administration, Sublingual, Adult, Ambulatory Care, Buprenorphine, Combined Modality Therapy, Connecticut, Counseling, Dose-Response Relationship, Drug, Drug Administration Schedule, Feasibility Studies, Female, Heroin Dependence, Humans, Male, Middle Aged, Primary Health Care, Social Support, Treatment Outcome, Urban Population},
	issn = {0095-2990},
	doi = {10.1111/j.1475-6773.2011.01335.x},
	author = {Fiellin, David A and Pantalon, Michael V and Pakes, Juliana P and O{\textquoteright}Connor, Patrick G and Chawarski, Marek and Schottenfeld, Richard S}
}
