@article {1997,
	title = {Can life expectancy and QALYs be improved by a framework for deciding whether to apply clinical guidelines to patients with severe comorbid disease?},
	journal = {Medical decision making : an international journal of the Society for Medical Decision Making},
	volume = {31},
	year = {2011},
	month = {2011 Jul-Aug},
	pages = {582-95},
	abstract = {Guidelines with short-term harms and long-term benefits are often applied to chronically ill patients who may not benefit. The payoff time framework has been proposed (i.e., do not apply a guideline if a patient{\textquoteright}s life expectancy (LE) is shorter than when a guideline{\textquoteright}s cumulative incremental benefits first exceed its cumulative incremental harms), but its health impact is unclear.},
	keywords = {Blood Glucose, Colorectal Neoplasms, Comorbidity, Female, Humans, Life Expectancy, Middle Aged, Models, Theoretical, Practice Guidelines as Topic, Quality-Adjusted Life Years},
	issn = {1552-681X},
	doi = {10.1186/1758-2652-14-38},
	author = {Braithwaite, R Scott}
}
