@article {3025,
	title = {Do benefits of earlier antiretroviral treatment initiation outweigh harms for individuals at risk for poor adherence?},
	journal = {Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
	volume = {48},
	year = {2009},
	month = {2009 Mar 15},
	pages = {822-6},
	abstract = {Clinicians may defer antiretroviral treatment for patients with suboptimal adherence. We used a validated computer simulation of HIV disease progression to compare alternative treatment thresholds for patients with suboptimal adherence. Earlier treatment increased life expectancy across a wide adherence range (50\%-100\% of doses taken). Delaying treatment for patients with suboptimal adherence may not always be appropriate.},
	keywords = {Adult, Antiviral Agents, Computer Simulation, HIV Infections, Humans, Life Expectancy, Medication Adherence, Middle Aged, Time Factors, Treatment Outcome},
	issn = {1537-6591},
	doi = {10.1086/528859},
	author = {Braithwaite, R Scott and Roberts, Mark S and Goetz, Matthew Bidwell and Gibert, Cynthia L and Rodriguez-Barradas, Maria C and Nucifora, Kimberly and Justice, Amy C}
}
