@article {4222, title = {Efficacy and day 7 plasma piperaquine concentrations in african children treated for uncomplicated malaria with dihydroartemisinin-piperaquine.}, journal = {PloS one}, volume = {9}, year = {2014}, month = {2014}, pages = {e103200}, abstract = {One promising new Artemisinin-based combination therapies (ACTs) is dihydroartemisinin-piperaquine (DHA-PQ). However, the pharmacokinetics of piperaquine and the relationship between drug levels and clinical efficacy are incompletely characterized, particularly in children.}, issn = {1932-6203}, doi = {10.1371/journal.pone.0103200}, author = {Zongo, Issaka and Som{\'e}, Fabrice A and Somda, Serge A M and Parikh, Sunil and Rouamba, Noel and Rosenthal, Philip J and Tarning, Joel and Lindegardh, Niklas and Nosten, Fran{\c c}ois and Ou{\'e}draogo, Jean Bosco} }