%0 Journal Article %J Vaccine %D 2011 %T The potential impact of an HIV vaccine with rapidly waning protection on the epidemic in Southern Africa: examining the RV144 trial results. %A Andersson, Kyeen M %A Paltiel, A David %A Owens, Douglas K %K Adolescent %K Adult %K AIDS Vaccines %K Clinical Trials as Topic %K Computer Simulation %K Condoms %K Female %K HIV %K HIV Infections %K Humans %K Immunization Programs %K Immunization, Secondary %K Male %K Prevalence %K Sexual Behavior %K South Africa %K Treatment Outcome %K Young Adult %N 36 %P 6107-12 %R 10.1097/QAI.0b013e3181fbc94f %V 29 %X The prime-boost HIV vaccine regimen used in the recent RV144 trial resulted in modest efficacy of 31% over 3.5 years, but was substantially higher in the first year post-vaccination. We sought to explore the potential impact of a vaccine with rapidly waning efficacy in a South African population. %8 2011 Aug 18