%0 Journal Article %J Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases %D 2013 %T Association betweenTLR3 rs3775291 and resistance to HIV among highly exposed Caucasian intravenous drug users. %A Huik, Kristi %A Avi, Radko %A Pauskar, Merit %A Kallas, Eveli %A Jõgeda, Ene-Ly %A Karki, Tõnis %A Marsh, Kristina %A Jarlais, Don Des %A Uusküla, Anneli %A Lutsar, Irja %R 10.1111/milq.12017 %X TLR3 recognizes dsRNA and triggers immune responses against RNA and DNA viruses. A polymorphism in TLR3, rs3775291 (Leu412Phe), has been associated with the increased susceptibility to enteroviral myocarditis, protection against tick-borne encephalitis virus and HIV-1 infection. We investigated Caucasian intravenous drug users (IDUs) and blood donors in order to evaluate the associations between TLR3 genotypes and susceptibility to HIV infection. %8 2013 Aug 17