%0 Journal Article %J JAMA internal medicine %D 2014 %T Primary Care-Based Buprenorphine Taper vs Maintenance Therapy for Prescription Opioid Dependence: A Randomized Clinical Trial. %A Fiellin, David A %A Schottenfeld, Richard S %A Cutter, Christopher J %A Moore, Brent A %A Barry, Declan T %A O'Connor, Patrick G %R 10.1001/jamainternmed.2014.5302 %X Prescription opioid dependence is increasing and creates a significant public health burden, but primary care physicians lack evidence-based guidelines to decide between tapering doses followed by discontinuation of buprenorphine hydrochloride and naloxone hydrochloride therapy (hereinafter referred to as buprenorphine therapy) or ongoing maintenance therapy. %8 2014 Oct 20