%0 Journal Article %J The lancet. HIV %D 2015 %T Comparative effectiveness of immediate antiretroviral therapy versus CD4-based initiation in HIV-positive individuals in high-income countries: observational cohort study. %A Lodi, Sara %A Phillips, Andrew %A Logan, Roger %A Olson, Ashley %A Costagliola, Dominique %A Abgrall, Sophie %A van Sighem, Ard %A Reiss, Peter %A Miró, José M %A Ferrer, Elena %A Justice, Amy %A Gandhi, Neel %A Bucher, Heiner C %A Furrer, Hansjakob %A Moreno, Santiago %A Monge, Susana %A Touloumi, Giota %A Pantazis, Nikos %A Sterne, Jonathan %A Young, Jessica G %A Meyer, Laurence %A Seng, Rémonie %A Dabis, Francois %A Vandehende, Marie-Anne %A Pérez-Hoyos, Santiago %A Jarrín, Inma %A Jose, Sophie %A Sabin, Caroline %A Hernán, Miguel A %N 8 %P e335-43 %R 10.1016/S2352-3018(15)00108-3 %V 2 %X Recommendations have differed nationally and internationally with respect to the best time to start antiretroviral therapy (ART). We compared effectiveness of three strategies for initiation of ART in high-income countries for HIV-positive individuals who do not have AIDS: immediate initiation, initiation at a CD4 count less than 500 cells per μL, and initiation at a CD4 count less than 350 cells per μL. %8 2015 Aug