| Title | Influence of interleukin 10 polymorphisms -592 and -1082 to the HIV, HBV and HCV serostatus among intravenous drug users. |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Kallas, Eveli, Kristi Huik, Merit Pauskar, Ene-Ly Jõgeda, Tõnis Karki, Don Des Jarlais, Anneli Uusküla, Radko Avi, and Irja Lutsar |
| Journal | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases |
| Volume | 30 |
| Pagination | 175-80 |
| Date Published | 2015 Mar |
| ISSN | 1567-7257 |
| Keywords | Adult, Cross-Sectional Studies, Drug Users, Female, Genetic Predisposition to Disease, Hepatitis B, Hepatitis C, HIV Infections, Humans, Interleukin-10, Male, Polymorphism, Genetic, Seroepidemiologic Studies, Substance Abuse, Intravenous, Young Adult |
| Abstract | Interleukin 10 (IL-10) is a multifunctional cytokine produced by macrophages, monocytes, and T-helper cells. Two polymorphisms at positions -592 and -1082 have been associated with HIV susceptibility. However, their associations with susceptibility to HIV and its co-infections among intravenous drug users (IDUs) are largely unknown. |
| DOI | 10.1016/j.meegid.2014.12.023 |
| Alternate Journal | Infect. Genet. Evol. |