Yale University

Influence of interleukin 10 polymorphisms -592 and -1082 to the HIV, HBV and HCV serostatus among intravenous drug users.

TitleInfluence of interleukin 10 polymorphisms -592 and -1082 to the HIV, HBV and HCV serostatus among intravenous drug users.
Publication TypeJournal Article
Year of Publication2015
AuthorsKallas, Eveli, Kristi Huik, Merit Pauskar, Ene-Ly Jõgeda, Tõnis Karki, Don Des Jarlais, Anneli Uusküla, Radko Avi, and Irja Lutsar
JournalInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Volume30
Pagination175-80
Date Published2015 Mar
ISSN1567-7257
KeywordsAdult, Cross-Sectional Studies, Drug Users, Female, Genetic Predisposition to Disease, Hepatitis B, Hepatitis C, HIV Infections, Humans, Interleukin-10, Male, Polymorphism, Genetic, Seroepidemiologic Studies, Substance Abuse, Intravenous, Young Adult
AbstractInterleukin 10 (IL-10) is a multifunctional cytokine produced by macrophages, monocytes, and T-helper cells. Two polymorphisms at positions -592 and -1082 have been associated with HIV susceptibility. However, their associations with susceptibility to HIV and its co-infections among intravenous drug users (IDUs) are largely unknown.
DOI10.1016/j.meegid.2014.12.023
Alternate JournalInfect. Genet. Evol.

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