| Title | The potential impact of an HIV vaccine with rapidly waning protection on the epidemic in Southern Africa: examining the RV144 trial results. |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Andersson, Kyeen M., David A. Paltiel, and Douglas K. Owens |
| Journal | Vaccine |
| Volume | 29 |
| Issue | 36 |
| Pagination | 6107-12 |
| Date Published | 2011 Aug 18 |
| ISSN | 1873-2518 |
| Keywords | Adolescent, Adult, AIDS Vaccines, Clinical Trials as Topic, Computer Simulation, Condoms, Female, HIV, HIV Infections, Humans, Immunization Programs, Immunization, Secondary, Male, Prevalence, Sexual Behavior, South Africa, Treatment Outcome, Young Adult |
| Abstract | The prime-boost HIV vaccine regimen used in the recent RV144 trial resulted in modest efficacy of 31% over 3.5 years, but was substantially higher in the first year post-vaccination. We sought to explore the potential impact of a vaccine with rapidly waning efficacy in a South African population. |
| DOI | 10.1097/QAI.0b013e3181fbc94f |
| Alternate Journal | Vaccine |
