| Title | The role of substance abuse in HIV disease progression: reconciling differences from laboratory and epidemiologic investigations. |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Kapadia, Farzana, David Vlahov, Robert M. Donahoe, and Gerald Friedland |
| Journal | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
| Volume | 41 |
| Issue | 7 |
| Pagination | 1027-34 |
| Date Published | 2005 Oct 1 |
| ISSN | 1537-6591 |
| Keywords | Animals, Disease Progression, HIV Infections, Humans, Substance-Related Disorders |
| Abstract | From the onset of the HIV/AIDS epidemic, the use of licit and illicit drugs has been investigated for its potential impact on HIV disease progression. Findings from a large number of laboratory-based studies indicate that drug abuse may exacerbate HIV disease progression; however, epidemiological studies have shown mixed results. This article presents a review of findings from both laboratory-based and epidemiologic investigations. In addition, we provide a careful evaluation of methodological strengths and limitations inherent to both study designs in order to provide a more nuanced understanding of how these findings may complement one another. |
| DOI | 10.3109/00952990.2011.568081 |
| Alternate Journal | Clin. Infect. Dis. |
