Yale University

Sandra Springer, M.D.

  • Associate professor of Medicine, Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine
  • Director, Infectious Disease Outpatient Clinic, Veterans Administration Healthcare Services, Newington
  • Member, Clinical and Health Services Research Core, CIRA
(203) 500-4057


Sandra Springer, M.D. is an Associate Professor of Medicine in the Department of Internal Medicine, Section of Infectious Diseases at the Yale School of Medicine. She is Board-Certified in Internal Medicine, Infectious Diseases and Addiction Medicine. Dr. Springer has significant research experience with adherence interventions for HIV-infected drug and alcohol dependent persons. She was a recipient of a NIDA-funded K23 mentored career development award, during which she evaluated the use of medication assisted treatment (MAT) to prevent relapse to opioid use as a conduit to care among HIV-infected opioid dependent released prisoners. She developed the first protocol to use Buprenorphine as relapse prevention for opioid dependent HIV+ prisoners on day of release and has published these findings that serve as proof of concept that MAT can be effective in maintaining HIV+ released prisoners HIV clinical outcomes. She also has expertise in supervising RCTs by serving as medical director and co-investigator for multiple RCTs including DAART adherence interventions for IDUs and HIV+ released prisoners. She also has considerable clinical and research experience with the use of extended-release Naltrexone and has been awarded an R01 from NIAAA as Principal Investigator to evaluate its use to prevent relapse to alcohol use among HIV infected alcohol dependent prisoners transitioning to the community, and from NIDA as PI as part of the Seek Test Treat and Retain initiative to evaluate its use to prevent relapse to opioid use among opioid dependent released criminal justice populations as a means to maintain HIV treatment outcomes. She is also a co-investigator on an R01 from NIDA with Dr. Altice evaluating the use of Buprenorphine as linkage to HIV testing and conduit to care for opioid dependent persons in Washington D.C. She has recently received a K02 independent scientist award from NIDA as well.  Dr. Springer has expertise in the development and implementation of medication-assisted-therapy interventions involving HIV+, drug and alcohol dependent persons involved in the criminal justice setting.

Selected Publications:

  • Rich, J.D., Wohl, D.A, Beckwith, C.G., Spaulding, A., Lepp, N.E., Baillargeon, J., Gardner, A., Avery, A,, Altice, F.L., Springer, S.A. “HIV-related research in correctional populations: Now is the time.” Current HIV/AIDS Reports (2011), Dec; 8 (4):288-296.

  • Springer, S.A., Azar, M.M., Altice, F.L. “HIV and alcohol dependence: A Call for evidence-based treatments for released prisoners.” American Journal of Drug and Alcohol Abuse (2010), December 21; 37(1); 12-21. [PMC3070290]

  • Meyer, J., Springer, S.A., Altice, F.L. “Substance abuse, violence, and HIV in women: A literature review of the syndemic.” Journal of Women’s Health (2011), May 2011; 20(7). [PMID:21668380]

  • Chen, N.E., Meyer, J.P., Springer, S.A. “Advances in the prevention of heterosexual transmission of HIV/AIDS among women in the United States.” Infectious Disease Reports (2011), 3:e6; 20-29.

  • Meyer, J.P., Chen, N.E., Springer, S.A. “HIV Treatment in the criminal justice system: Critical knowledge and intervention gaps.” AIDS Research and Treatment (2011) 680617. Epub 2011 Jul 12.

  • Chen NE, Meyer JP, Avery Ak, Draine J, Ph, Flanigan TP, Lincoln T, Spaulding AC, Springer SA, Altice FL. Adherence to HIV treatment and care among previously homeless jail detainees. AIDS and Behavior, 2011; Nov 8 (Epub ahead of print).(PMID: 22065234)

  • Springer SA, Spaulding AC, Meyer JP, Altice FL. Public Health Implications for Adequate Transitional Care for HIV-Infected Prisoners: Five Essential Components. Clinical Infectious Disease, 2011 53(5):469-479.

  • Springer SA. High rates of depressive Symptomatology among injecting drug users in Saskatoon, Canada. Evidence Based Mental Health. 2011 Nov 1. (Epub ahead of print).