Yale University

Adherence to antiretroviral therapy: an empirical test of the information-motivation-behavioral skills model.

TitleAdherence to antiretroviral therapy: an empirical test of the information-motivation-behavioral skills model.
Publication TypeJournal Article
Year of Publication2006
AuthorsStarace, Fabrizio, Alessandra Massa, Rivet K. Amico, and Jeffrey D. Fisher
JournalHealth psychology : official journal of the Division of Health Psychology, American Psychological Association
Date Published2006 Mar
KeywordsAdult, Aged, Anti-Retroviral Agents, Female, Health Surveys, Humans, Italy, Male, Middle Aged, Models, Theoretical, Motivation, Patient Compliance, Patient Education as Topic
AbstractConsistent and nearly perfect adherence is considered an essential requirement for HIV-positive patients on antiretroviral therapy (ART) to fully realize its life-extending benefits. The current study evaluated a comprehensive model of ART adherence--the information-motivation-behavioral skills (IMB) model. This model views adherence behavior as a function of the interrelations between adherence-related information, motivation, and behavioral skills. It hypothesizes that adherence-related information and motivation work through adherence-related behavioral skills to affect the initiation and maintenance of optimal ART adherence. In a series of structural equation models, the IMB model's critical constructs and assumptions were evaluated with a sample of 100 HIV-positive patients in clinical care. Across all analyses, the authors found support for the assumptions of the IMB model of ART adherence. Consistent with the model, adherence-related information and motivation related significantly to adherence-related behavioral skills, and behavioral skills related significantly to self-reported optimal adherence. Further, as predicted, the effects of information and motivation on self-reported adherence were mediated by adherence-related behavioral skills. Current study results are explored, and implications for adherence promotion interventions based on the model are discussed.
Alternate JournalHealth Psychol

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