| Title | Detailed analysis of immunologic effects of the cytotoxic T lymphocyte-associated antigen 4-blocking monoclonal antibody tremelimumab in peripheral blood of patients with melanoma. |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Comin-Anduix, Begoña, Yohan Lee, Jason Jalil, Alain Algazi, Pilar de la Rocha, Luis H. Camacho, Viviana A. Bozon, Cecile A. Bulanhagui, Elisabeth Seja, Arturo Villanueva, Bradley R. Straatsma, Antonio Gualberto, James S. Economou, John A. Glaspy, Jesus Gomez-Navarro, and Antoni Ribas |
| Journal | Journal of translational medicine |
| Volume | 6 |
| Pagination | 22 |
| Date Published | 2008 |
| ISSN | 1479-5876 |
| Keywords | Adult, Aged, Aged, 80 and over, Antibodies, Monoclonal, Antigens, CD, Cluster Analysis, CTLA-4 Antigen, Female, HLA-A Antigens, HLA-A2 Antigen, Humans, Immune System, Male, Melanoma, Middle Aged, T-Lymphocytes |
| Abstract | CTLA4-blocking antibodies induce tumor regression in a subset of patients with melanoma. Analysis of immune parameters in peripheral blood may help define how responses are mediated. |
| DOI | 10.1086/528859 |
| Alternate Journal | J Transl Med |
