Title | Developing a modified directly observed therapy intervention for hepatitis C treatment in a methadone maintenance program: implications for program replication. |
Publication Type | Journal Article |
Year of Publication | 2012 |
Authors | Bruce, Douglas R., Julie Eiserman, Angela Acosta, Ceilia Gote, Joseph K. Lim, and Frederick L. Altice |
Journal | The American journal of drug and alcohol abuse |
Volume | 38 |
Issue | 3 |
Pagination | 206-12 |
Date Published | 2012 May |
ISSN | 1097-9891 |
Keywords | Adult, Antiviral Agents, Directly Observed Therapy, Female, Hepacivirus, Hepatitis C, Humans, Interferon-alpha, Male, Medication Adherence, Methadone, Middle Aged, Opiate Substitution Treatment, Opioid-Related Disorders, Pilot Projects, Polyethylene Glycols, Recombinant Proteins, Ribavirin, Self Administration, Viral Load |
Abstract | Hepatitis C virus (HCV) is a prevalent chronic blood-borne infection among opioid-dependent patients on methadone maintenance treatment (MMT). Despite case reports and case-control studies, a randomized controlled trial (RCT) examining HCV treatment adherence in methadone-maintained patients is lacking and was the impetus for this ongoing RCT examining modified directly administered therapy for HCV treatment integrated within a MMT. |
DOI | 10.1097/QAI.0b013e3181fbc94f |
Alternate Journal | Am J Drug Alcohol Abuse |