Title | Do Biomarkers Of Inflammation, Monocyte Activation And Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People? |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | So-Armah, Kaku A., Janet P. Tate, Chung-Chou H. Chang, Adeel A. Butt, Mariana Gerschenson, Cynthia L. Gibert, David Leaf, David Rimland, Maria C. Rodriguez-Barradas, Matthew J. Budoff, Jeffrey H. Samet, Lewis H. Kuller, Steven G. Deeks, Kristina A. Crothers, Russell P. Tracy, Heidi M. Crane, Mohammad M. Sajadi, Hilary A. Tindle, Amy C. Justice, and Matthew S. Freiberg |
Corporate Authors | the VACS Project Team |
Journal | Journal of acquired immune deficiency syndromes (1999) |
Date Published | 2016 Feb 13 |
ISSN | 1944-7884 |
Abstract | HIV infection and biomarkers of inflammation (measured by interleukin-6 [IL-6]), monocyte activation (soluble CD14 [sCD14]), and coagulation (D-dimer) are associated with morbidity and mortality. We hypothesized that these immunologic processes mediate (explain) some of the excess risk of mortality among HIV infected (HIV+) versus uninfected people independently of co-morbid diseases. |
Alternate Journal | J. Acquir. Immune Defic. Syndr. |