Yale University

Do Biomarkers Of Inflammation, Monocyte Activation And Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People?

TitleDo Biomarkers Of Inflammation, Monocyte Activation And Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People?
Publication TypeJournal Article
Year of Publication2016
AuthorsSo-Armah, Kaku A., Janet P. Tate, Chung-Chou H. Chang, Adeel A. Butt, Mariana Gerschenson, Cynthia L. Gibert, David Leaf, David Rimland, Maria C. Rodriguez-Barradas, Matthew J. Budoff, Jeffrey H. Samet, Lewis H. Kuller, Steven G. Deeks, Kristina A. Crothers, Russell P. Tracy, Heidi M. Crane, Mohammad M. Sajadi, Hilary A. Tindle, Amy C. Justice, and Matthew S. Freiberg
Corporate Authorsthe VACS Project Team
JournalJournal of acquired immune deficiency syndromes (1999)
Date Published2016 Feb 13
ISSN1944-7884
AbstractHIV infection and biomarkers of inflammation (measured by interleukin-6 [IL-6]), monocyte activation (soluble CD14 [sCD14]), and coagulation (D-dimer) are associated with morbidity and mortality. We hypothesized that these immunologic processes mediate (explain) some of the excess risk of mortality among HIV infected (HIV+) versus uninfected people independently of co-morbid diseases.
Alternate JournalJ. Acquir. Immune Defic. Syndr.

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