| Title | Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine. |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Zongo, Issaka, Fabrice A. Somé, Serge A. M. Somda, Sunil Parikh, Noel Rouamba, Philip J. Rosenthal, Joel Tarning, Niklas Lindegardh, François Nosten, and Jean Bosco Ouédraogo |
| Journal | PloS one |
| Volume | 9 |
| Issue | 8 |
| Pagination | e103200 |
| Date Published | 2014 |
| ISSN | 1932-6203 |
| Keywords | Antimalarials, Artemisinins, Burkina Faso, Child, Child, Preschool, Drug Administration Schedule, Drug Combinations, Female, Humans, Infant, Malaria, Falciparum, Male, Quinolines, Treatment Failure |
| Abstract | One promising new Artemisinin-based combination therapies (ACTs) is dihydroartemisinin-piperaquine (DHA-PQ). However, the pharmacokinetics of piperaquine and the relationship between drug levels and clinical efficacy are incompletely characterized, particularly in children. |
| DOI | 10.1371/journal.pone.0103200 |
| Alternate Journal | PLoS ONE |
