Title | HIV coinfection in multidrug- and extensively drug-resistant tuberculosis results in high early mortality. |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Gandhi, Neel R., Sarita N. Shah, Jason R. Andrews, Venanzio Vella, Anthony P. Moll, Michelle Scott, Darren Weissman, Claudio Marra, Umesh G. Lalloo, and Gerald H. Friedland |
Corporate Authors | Tugela Ferry Care and Research(TF CARES) Collaboration |
Journal | American journal of respiratory and critical care medicine |
Volume | 181 |
Issue | 1 |
Pagination | 80-6 |
Date Published | 2010 Jan 1 |
ISSN | 1535-4970 |
Keywords | Adult, Extensively Drug-Resistant Tuberculosis, Female, HIV Infections, Humans, Kaplan-Meier Estimate, Male, South Africa |
Abstract | The multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) epidemics are rapidly expanding in South Africa. Our initial report of HIV-associated XDR TB in South Africa revealed rapid and near complete mortality. Lower mortality has been described in the literature, but few of these patients have been HIV coinfected. |
DOI | 10.1164/rccm.200907-0989OC |
Alternate Journal | Am. J. Respir. Crit. Care Med. |