Yale University

The impact of comprehensive prevention of mother-to-child HIV transmission in Dehong prefecture, Yunnan province, 2005-2010: a hard-hit area by HIV in Southern China.

TitleThe impact of comprehensive prevention of mother-to-child HIV transmission in Dehong prefecture, Yunnan province, 2005-2010: a hard-hit area by HIV in Southern China.
Publication TypeJournal Article
Year of Publication2014
AuthorsShan, Duo, Jiangping Sun, Kaveh Khoshnood, Jeannia Fu, Song Duan, Chengqin Jiang, Yan Zhang, Marc Bulterys, Haoyan Guo, Michael Sante, Hui Liu, and Yiyun Hu
JournalInternational journal of STD & AIDS
Volume25
Issue4
Pagination253-60
Date Published2014 Mar
ISSN1758-1052
KeywordsAnti-HIV Agents, Child, China, Epidemics, Female, Health Services Accessibility, HIV Infections, HIV-1, Humans, Infectious Disease Transmission, Vertical, Mass Screening, Mothers, Pregnancy, Pregnancy Complications, Infectious, Prevalence, Program Evaluation
AbstractThe burden of HIV/AIDS in China has been disproportionately concentrated in Yunnan Province, where in Dehong prefecture, the HIV prevalence rate among pregnant women reached 1.3% in 2003, a rate that is indicative of a generalized epidemic. Since then, there have been extensive efforts to expand prevention to reduce mother-to-child transmission (MTCT) in this high-prevalence region. These intensified MTCT reduction efforts and their impact on MTCT are yet to be examined. We described the changes in access to HIV screening and antiretroviral therapy (ART) among pregnant women from 2005 to 2010 in this region and the corresponding reduction in MTCT over this period. Between 2005 and 2010, the annual number of pregnant women screened for HIV in Dehong Prefecture more than doubled. The proportion of pregnant women screened for HIV rose from an estimated 15-20% to 99.8%, and the proportion of HIV-infected pregnant women receiving ART increased from 63% to 99%. We estimate that the proportion of children born with HIV to HIV-infected mothers decreased from 15.4% to 7.2% over this period. Sustained low-level MTCT following comprehensive interventions in this region is encouraging. Over the last decade, comprehensive PMTCT efforts, coupled with national and local government policy support in this area appear to be effective.
DOI10.1177/0956462413499010
Alternate JournalInt J STD AIDS

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