Yale University

Increasing drug resistance in extensively drug-resistant tuberculosis, South Africa.

TitleIncreasing drug resistance in extensively drug-resistant tuberculosis, South Africa.
Publication TypeJournal Article
Year of Publication2011
AuthorsShah, Sarita N., Jessica Richardson, Prashini Moodley, Salona Moodley, Palav Babaria, Melissa Ramtahal, Scott K. Heysell, Xuan Li, Anthony P. Moll, Gerald Friedland, Willem A. Sturm, and Neel R. Gandhi
JournalEmerging infectious diseases
Date Published2011 Mar
KeywordsAdult, Antitubercular Agents, Drug Resistance, Multiple, Bacterial, Extensively Drug-Resistant Tuberculosis, Female, Humans, Male, Microbial Sensitivity Tests, Middle Aged, Mycobacterium tuberculosis, South Africa, Tuberculosis, Multidrug-Resistant, Young Adult
AbstractWe expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa. Of 19 patients with extensively drug-resistant TB identified during February 2008-April 2009, 13 (68%) had isolates resistant to all 8 drugs tested. This resistance leaves no effective treatment with available drugs in South Africa.
Alternate JournalEmerging Infect. Dis.

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