| Title | Predictors of multidrug- and extensively drug-resistant tuberculosis in a high HIV prevalence community. |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Andrews, Jason R., Sarita N. Shah, Darren Weissman, Anthony P. Moll, Gerald Friedland, and Neel R. Gandhi |
| Journal | PloS one |
| Volume | 5 |
| Issue | 12 |
| Pagination | e15735 |
| Date Published | 2010 |
| ISSN | 1932-6203 |
| Keywords | Adult, Case-Control Studies, Communicable Disease Control, Extensively Drug-Resistant Tuberculosis, Female, HIV Infections, Humans, Male, Odds Ratio, Prevalence, Retrospective Studies, Risk, Risk Factors, South Africa, Tuberculosis, Multidrug-Resistant |
| Abstract | Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) have emerged in high-HIV-prevalence settings, which generally lack laboratory infrastructure for diagnosing TB drug resistance. Even where available, inherent delays with current drug-susceptibility testing (DST) methods result in clinical deterioration and ongoing transmission of MDR and XDR-TB. Identifying clinical predictors of drug resistance may aid in risk stratification for earlier treatment and infection control. |
| DOI | 10.1007/s11606-010-1323-z |
| Alternate Journal | PLoS ONE |
