Title | A randomized controlled trial of highly active antiretroviral therapy versus highly active antiretroviral therapy and chemotherapy in therapy-naive patients with HIV-associated Kaposi sarcoma in South Africa. |
Publication Type | Journal Article |
Year of Publication | 2012 |
Authors | Mosam, Anisa, Fahmida Shaik, Thomas S. Uldrick, Tonya Esterhuizen, Gerald H. Friedland, David T. Scadden, Jamila Aboobaker, and Hoosen M. Coovadia |
Journal | Journal of acquired immune deficiency syndromes (1999) |
Volume | 60 |
Issue | 2 |
Pagination | 150-7 |
Date Published | 2012 Jun 1 |
ISSN | 1944-7884 |
Keywords | Adult, Anti-HIV Agents, Antigens, Neoplasm, Antiretroviral Therapy, Highly Active, Drug Therapy, Female, Humans, Lamivudine, Male, Nevirapine, Sarcoma, Kaposi, South Africa, Stavudine, Survival Analysis, Treatment Outcome |
Abstract | The optimal approach to HIV-associated Kaposi sarcoma (HIV-KS) in sub-Saharan Africa is unknown. With large-scale rollout of highly active antiretroviral therapy (HAART) in South Africa, we hypothesized that survival in HIV-KS would improve and administration of chemotherapy in addition to HAART would be feasible and improve KS-specific outcomes. |
DOI | 10.1097/QAI.0b013e318251aedd |
Alternate Journal | J. Acquir. Immune Defic. Syndr. |