Yale University

A randomized controlled trial of highly active antiretroviral therapy versus highly active antiretroviral therapy and chemotherapy in therapy-naive patients with HIV-associated Kaposi sarcoma in South Africa.

TitleA randomized controlled trial of highly active antiretroviral therapy versus highly active antiretroviral therapy and chemotherapy in therapy-naive patients with HIV-associated Kaposi sarcoma in South Africa.
Publication TypeJournal Article
Year of Publication2012
AuthorsMosam, Anisa, Fahmida Shaik, Thomas S. Uldrick, Tonya Esterhuizen, Gerald H. Friedland, David T. Scadden, Jamila Aboobaker, and Hoosen M. Coovadia
JournalJournal of acquired immune deficiency syndromes (1999)
Volume60
Issue2
Pagination150-7
Date Published2012 Jun 1
ISSN1944-7884
KeywordsAdult, Anti-HIV Agents, Antigens, Neoplasm, Antiretroviral Therapy, Highly Active, Drug Therapy, Female, Humans, Lamivudine, Male, Nevirapine, Sarcoma, Kaposi, South Africa, Stavudine, Survival Analysis, Treatment Outcome
AbstractThe optimal approach to HIV-associated Kaposi sarcoma (HIV-KS) in sub-Saharan Africa is unknown. With large-scale rollout of highly active antiretroviral therapy (HAART) in South Africa, we hypothesized that survival in HIV-KS would improve and administration of chemotherapy in addition to HAART would be feasible and improve KS-specific outcomes.
DOI10.1097/QAI.0b013e318251aedd
Alternate JournalJ. Acquir. Immune Defic. Syndr.

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