Title | Rapid diagnosis of tuberculosis and multidrug resistance by the microscopic-observation drug-susceptibility assay. |
Publication Type | Journal Article |
Year of Publication | 2011 |
Authors | Shah, Sarita N., Prashini Moodley, Palav Babaria, Salona Moodley, Melissa Ramtahal, Jessica Richardson, Scott Heysell, Xuan Li, Anthony Moll, Gerald Friedland, Willem A. Sturm, and Neel R. Gandhi |
Journal | American journal of respiratory and critical care medicine |
Volume | 183 |
Issue | 10 |
Pagination | 1427-33 |
Date Published | 2011 May 15 |
ISSN | 1535-4970 |
Keywords | Adult, Antitubercular Agents, Female, HIV Infections, Humans, Male, Microbial Sensitivity Tests, Middle Aged, Mycobacterium tuberculosis, Prospective Studies, Reproducibility of Results, Sensitivity and Specificity, South Africa, Sputum, Tuberculosis, Tuberculosis, Multidrug-Resistant |
Abstract | Mortality is exceedingly high and rapid among patients infected with HIV and tuberculosis (TB), in part because of limited access to appropriate TB diagnostics. The microscopic observation drug-susceptibility (MODS) assay is a simple, rapid, low-cost test for TB and multidrug-resistant (MDR) TB, but data in individuals infected with HIV and in Africa are limited. |
DOI | 10.1164/rccm.201009-1449OC |
Alternate Journal | Am. J. Respir. Crit. Care Med. |