| Title | Rifampin, but not rifabutin, may produce opiate withdrawal in buprenorphine-maintained patients. |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | McCance-Katz, Elinore F., David E. Moody, Sudha Prathikanti, Gerald Friedland, and Petrie M. Rainey |
| Journal | Drug and alcohol dependence |
| Volume | 118 |
| Issue | 2-3 |
| Pagination | 326-34 |
| Date Published | 2011 Nov 1 |
| ISSN | 1879-0046 |
| Keywords | Adult, Antitubercular Agents, Buprenorphine, Drug Interactions, Female, Humans, Male, Middle Aged, Narcotic Antagonists, Opiate Substitution Treatment, Opioid-Related Disorders, Rifabutin, Rifampin, Substance Withdrawal Syndrome |
| Abstract | This series of studies examines the pharmacokinetic/pharmacodynamic interactions between buprenorphine, an opioid partial agonist increasingly used in treatment of opioid dependence, and rifampin, a medication used as a first line treatment for tuberculosis; or rifabutin, an alternative antituberculosis medication. |
| DOI | 10.3109/00952990.2011.568081 |
| Alternate Journal | Drug Alcohol Depend |
