| Title | Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza. |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Bermejo-Martin, Jesus F., Raul Ortiz de Lejarazu, Tomas Pumarola, Jordi Rello, Raquel Almansa, Paula Ramírez, Ignacio Martin-Loeches, David Varillas, Maria C. Gallegos, Carlos Serón, Dariela Micheloud, Jose Manuel Gomez, Alberto Tenorio-Abreu, María J. Ramos, Lourdes M. Molina, Samantha Huidobro, Elia Sanchez, Mónica Gordón, Victoria Fernández, Alberto Del Castillo, Ma Angeles Marcos, Beatriz Villanueva, Carlos Javier López, Mario Rodríguez-Domínguez, Juan-Carlos Galan, Rafael Cantón, Aurora Lietor, Silvia Rojo, Jose M. Eiros, Carmen Hinojosa, Isabel Gonzalez, Nuria Torner, David Banner, Alberto Leon, Pablo Cuesta, Thomas Rowe, and David J. Kelvin |
| Journal | Critical care (London, England) |
| Volume | 13 |
| Issue | 6 |
| Pagination | R201 |
| Date Published | 2009 |
| ISSN | 1466-609X |
| Keywords | Adult, Chemokines, Cytokines, DNA Primers, Female, Hemagglutination Inhibition Tests, Humans, Influenza A Virus, H1N1 Subtype, Influenza, Human, Intensive Care Units, Length of Stay, Male, Middle Aged, Patient Selection, RNA, Viral, Severity of Illness Index, Th1 Cells, Viral Load |
| Abstract | Human host immune response following infection with the new variant of A/H1N1 pandemic influenza virus (nvH1N1) is poorly understood. We utilize here systemic cytokine and antibody levels in evaluating differences in early immune response in both mild and severe patients infected with nvH1N1. |
| DOI | 10.1353/hpu.2012.0006 |
| Alternate Journal | Crit Care |
