| Title | Time for change? An economic evaluation of integrated cervical screening and HPV immunization programs in Canada. |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Tully, Stephen P., Andrea M. Anonychuk, Diana Maria Sanchez, Alison P. Galvani, and Chris T. Bauch |
| Journal | Vaccine |
| Volume | 30 |
| Issue | 2 |
| Pagination | 425-35 |
| Date Published | 2012 Jan 5 |
| ISSN | 1873-2518 |
| Abstract | Many jurisdictions have implemented universal human papillomavirus (HPV) immunization programs in preadolescent females. However, the cost-effectiveness of modified cervical screening guidelines and/or catch-up immunization in older females in Canada has not been evaluated. We conducted a cost-utility analysis of screening and immunization with the bivalent vaccine for the Canadian setting from the Ministry of Health perspective. We used a dynamic model to capture herd immunity and included cross-protection against strains not included in the vaccine. We found that adding catch-up immunization to the current program would be cost-effective, and that combining catch-up immunization with delaying the age at which screening is first initiated could result in cost savings and net health gains. |
| Alternate Journal | Vaccine |
