Yale University

Predicting survival among those aging with HIV infection

A new collaborative study led by Yale, the VA Healthcare System, and the North American Cohort Collaboration supports the accuracy of an index used for predicting mortality as patients with HIV age. The study appears in the Journal of Acquired Immune Deficiency Syndromes (JAIDS).

The course of chronic HIV infection has changed with the advent of antiretroviral therapy (ART). Viral suppression is common, the authors write, and there have been reductions in AIDS-related deaths in regions where ART is easily accessible. Yet, the authors say, people with HIV infection continue to experience a higher rate of mortality due not just to HIV-related factors, but because chronic HIV infection appears to exacerbate vulnerability to aging-related organ system injury.



Published: Tuesday, February 5, 2013