| Title | Absolute CD4+ T-lymphocyte count as a surrogate marker of pediatric human immunodeficiency virus disease progression. |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Paintsil, Elijah, Musie Ghebremichael, Sostena Romano, and Warren A. Andiman |
| Journal | The Pediatric infectious disease journal |
| Volume | 27 |
| Issue | 7 |
| Pagination | 629-35 |
| Date Published | 2008 Jul |
| ISSN | 0891-3668 |
| Keywords | Adolescent, Biological Markers, CD4 Lymphocyte Count, CD4-Positive T-Lymphocytes, Child, Child, Preschool, Disease Progression, Female, HIV, HIV Infections, Humans, Longitudinal Studies, Lymphocyte Count, Male, Viral Load |
| Abstract | Traditionally in pediatric HIV, the CD4+ T-lymphocyte percent is used to monitor disease progression because of the variability in absolute CD4+ T-lymphocyte numbers. Because of the high cost of equipment, sophisticated and delicate technology, most laboratories in resource-limited settings use simple protocols that enumerate only the absolute CD4+ T-lymphocyte counts. We assessed the use of absolute CD4+ T-lymphocyte count as a surrogate marker of pediatric HIV disease progression. |
| DOI | 10.1086/528859 |
| Alternate Journal | Pediatr. Infect. Dis. J. |
