Yale University

Alcohol and adherence to antiretroviral medications: interactive toxicity beliefs among people living with HIV.

TitleAlcohol and adherence to antiretroviral medications: interactive toxicity beliefs among people living with HIV.
Publication TypeJournal Article
Year of Publication2012
AuthorsKalichman, Seth C., Christina M. Amaral, Denise White, Connie Swetsze, Moira O. Kalichman, Chauncey Cherry, and Lisa Eaton
JournalThe Journal of the Association of Nurses in AIDS Care : JANAC
Volume23
Issue6
Pagination511-20
Date Published2012 Nov
ISSN1552-6917
KeywordsAlcohol Drinking, Anti-HIV Agents, HIV Infections, Humans, Patient Compliance, United States
AbstractWhen taken without interruption, antiretroviral therapies (ART) effectively treat HIV infection. Alcohol is a well-known direct and indirect influence on ART adherence. Believing that drinking is harmful while taking ART (interactive toxicity beliefs) is also associated with poor adherence. The current study included 333 people living with HIV who were taking ART and actively using alcohol. Participants were recruited from health care providers and social services in a major southern U.S. city. Results showed that 52% of persons found non-adherent to ART stated that they stopped taking their medications when they were drinking. Multivariate analyses showed that interrupting treatment when drinking was related to current non-adherence, over and above several common correlates of non-adherence including frequency of alcohol use itself. These results confirm and extend past research, indicating an urgent need for medication adherence interventions designed for people living with HIV who drink.
DOI10.1016/j.amepre.2009.08.027
Alternate JournalJ Assoc Nurses AIDS Care

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