| Title | Brief behavioral self-regulation counseling for HIV treatment adherence delivered by cell phone: an initial test of concept trial. |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Kalichman, Seth C., Moira O. Kalichman, Chauncey Cherry, Connie Swetzes, Christina M. Amaral, Denise White, Mich'l Jones, Tamar Grebler, and Lisa Eaton |
| Journal | AIDS patient care and STDs |
| Volume | 25 |
| Issue | 5 |
| Pagination | 303-10 |
| Date Published | 2011 May |
| ISSN | 1557-7449 |
| Keywords | Adult, Aged, Cellular Phone, Counseling, Drug Administration Schedule, Female, Follow-Up Studies, HIV Infections, Humans, Intervention Studies, Male, Medication Adherence, Middle Aged, Self Care, Self Efficacy, Social Control, Informal, Socioeconomic Factors, Treatment Outcome |
| Abstract | Affordable and effective antiretroviral therapy (ART) adherence interventions are needed for many patients to promote positive treatment outcomes and prevent viral resistance. We conducted a two-arm randomized trial (n = 40 men and women receiving and less than 95% adherent to ART) to test a single office session followed by four biweekly cell phone counseling sessions that were grounded in behavioral self-management model of medication adherence using data from phone-based unannounced pill counts to provide feedback-guided adherence strategies. The control condition received usual care and matched office and cell phone/pill count contacts. Participants were baseline assessed and followed with biweekly unannounced pill counts and 4-month from baseline computerized interviews (39/40 retained). Results showed that the self-regulation counseling delivered by cell phone demonstrated significant improvements in adherence compared to the control condition; adherence improved from 87% of pills taken at baseline to 94% adherence 4 months after baseline, p < 0.01. The observed effect sizes ranged from moderate (d = 0.45) to large (d = 0.80). Gains in adherence were paralleled with increased self-efficacy (p < 0.05) and use of behavioral strategies for ART adherence (p < 0.05). We conclude that the outcomes from this test of concept trial warrant further research on cell phone-delivered self-regulation counseling in a larger and more rigorous trial. |
| DOI | 10.1089/apc.2010.0367 |
| Alternate Journal | AIDS Patient Care STDS |
