Yale University

Cancer screening in patients infected with HIV.

TitleCancer screening in patients infected with HIV.
Publication TypeJournal Article
Year of Publication2011
AuthorsSigel, Keith, Robert Dubrow, Michael Silverberg, Kristina Crothers, Scott Braithwaite, and Amy Justice
JournalCurrent HIV/AIDS reports
Date Published2011 Sep
KeywordsEarly Detection of Cancer, Female, HIV, HIV Infections, Humans, Male, Neoplasms
AbstractNon-AIDS-defining cancers are a rising health concern among HIV-infected patients. Cancer screening is now an important component of health maintenance in HIV clinical practice. The decision to screen an HIV-infected patient for cancer should include an assessment of individualized risk for the particular cancer, life expectancy, and the harms and benefits associated with the screening test and its potential outcome. HIV-infected patients are at enhanced risk of several cancers compared to the general population; anal cancer, hepatocellular carcinoma, Hodgkin's lymphoma, and lung cancer all have good evidence demonstrating an enhanced risk in HIV-infected persons. A number of cancer screening interventions have shown benefit for specific cancers in the general population, but data on the application of these tests to HIV-infected persons are limited. Here we review the epidemiology and background literature relating to cancer screening interventions in HIV-infected persons. We then use these data to inform a conceptual model for evaluating HIV-infected patients for cancer screening.
Alternate JournalCurr HIV/AIDS Rep

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