| Title | Determinants of high-risk sexual behavior during post-exposure prophylaxis to prevent HIV infection. |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Golub, Sarit A., Lisa Rosenthal, Daniel E. Cohen, and Kenneth H. Mayer |
| Journal | AIDS and behavior |
| Volume | 12 |
| Issue | 6 |
| Pagination | 852-9 |
| Date Published | 2008 Nov |
| ISSN | 1573-3254 |
| Keywords | Adenine, Anti-HIV Agents, Deoxycytidine, Drug Therapy, Combination, HIV Infections, Homosexuality, Male, Humans, Interviews as Topic, Lamivudine, Male, Organophosphonates, Questionnaires, Reverse Transcriptase Inhibitors, Risk Factors, Risk-Taking, Sexual Partners, Treatment Outcome |
| Abstract | Men who have sex with men (MSM) receiving non-occupational post-exposure prophylaxis (NPEP) to prevent HIV transmission completed interview-assisted questionnaires regarding high-risk behavior in the 6 months prior to NPEP and during the 28-day NPEP period. 21% of participants reported unprotected sex during NPEP, and 11% reported unprotected sex with HIV-positive or HIV status unknown partners. In univariate analyses, unprotected sex during NPEP was associated with prevention fatigue, depression, loss of loved ones to HIV, and a history of engagement with HIV/AIDS service organizations, e.g., receiving services from an HIV-related agency, donating money to HIV-related causes, and reading HIV-related magazines. Logistic regression analyses revealed that the strongest predictor of risk-taking during NPEP was HIV engagement. These data underscore the importance of combining chemoprophylaxis with behavioral interventions that support risk-reduction. Such interventions should not assume that those most engaged with HIV/AIDS service organizations are less likely to engage in risk behavior. |
| DOI | 10.1086/528859 |
| Alternate Journal | AIDS Behav |
