| Title | Estimating the rate of accumulating drug resistance mutations in the HIV genome. |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Braithwaite, Scott R., Steven Shechter, Chung-Chou H. Chang, Andrew Schaefer, and Mark S. Roberts |
| Journal | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research |
| Volume | 10 |
| Issue | 3 |
| Pagination | 204-13 |
| Date Published | 2007 May-Jun |
| ISSN | 1098-3015 |
| Keywords | Antiretroviral Therapy, Highly Active, Calibration, Computer Simulation, Drug Resistance, Viral, HIV, Humans, Monte Carlo Method, Mutation, Patient Compliance, Reproducibility of Results |
| Abstract | HIV mutation accumulation has great implications for pharmacoeconomics and clinical care, yet scarcity of data has hindered its representation in decision analytic models. Our objective is to determine the accuracy with which mutation accumulation and other unmeasured parameters could be estimated during model calibration. |
| DOI | 10.1186/1758-2652-14-38 |
| Alternate Journal | Value Health |
