Title | The feasibility of HIV vaccine efficacy trials among Russian injection drug users. |
Publication Type | Journal Article |
Year of Publication | 2007 |
Authors | Beyrer, Chris, Stefan Baral, Alla Shaboltas, Elena Dukhovlinova, Alexey Masharsky, Sergey Verevochkin, Carl Latkin, Robert Heimer, Irving Hoffman, and Andrei Kozlov |
Journal | Vaccine |
Volume | 25 |
Issue | 41 |
Pagination | 7014-6 |
Date Published | 2007 Oct 10 |
ISSN | 0264-410X |
Keywords | AIDS Vaccines, HIV, HIV Infections, Humans, Russia, Substance Abuse, Intravenous |
Abstract | IDU exposure remains a primary driver of the Russian HIV epidemic, and recent incidence data provide little evidence that this epidemic is slowing. While there are multiple important challenges that need to be further explored before starting vaccine trials, most importantly access to evidence-based drug treatment services for trial participants, the current context of high HIV incidence and low genetic diversity of HIV strains, suggests the need for intensified prevention strategies and supports the feasibility of mounting efficacy trials of HIV vaccines among IDUs in the Russian Federation. |
DOI | 10.1111/j.1360-0443.2010.03149.x |
Alternate Journal | Vaccine |