| Title | Generic antiretroviral efficacy in AIDS-associated Kaposi's sarcoma in sub-Saharan Africa. |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Mosam, Anisa, Edana Cassol, Taryn Page, Uvani Bodasing, Sharon Cassol, Halima Dawood, Gerald H. Friedland, David T. Scadden, Jamila Aboobaker, Jacobus P. Jordaan, Umesh G. Lalloo, Tonya M. Esterhuizen, and Hoosen M. Coovadia |
| Journal | AIDS (London, England) |
| Volume | 19 |
| Issue | 4 |
| Pagination | 441-3 |
| Date Published | 2005 Mar 4 |
| ISSN | 0269-9370 |
| Keywords | Acquired Immunodeficiency Syndrome, Africa South of the Sahara, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Developing Countries, Drugs, Generic, Humans, Sarcoma, Kaposi, Treatment Outcome, Viral Load |
| Abstract | Generic antiretroviral drugs are pivotal in the implementation of WHO's '3 by 5' programme. However, clinical experience with generics in sub-Saharan Africa is insufficiently documented. We report on 50 patients with HIV-associated Kaposi's sarcoma treated with generic fixed-dose highly active antiretroviral therapy. At 52 weeks, 74% achieved an undetectable viral load of < 50 copies/ml, 86% achieved < 400 copies/ml, and a 3.1 log10 decline from baseline. Side-effects were minimal. The outcomes support the use of generic antiretroviral therapy. |
| DOI | 10.3109/00952990.2011.568081 |
| Alternate Journal | AIDS |
