| Title | Long-term mortality in HIV-positive individuals virally suppressed for >3 years with incomplete CD4 recovery |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Engsig, Frederik N., Robert Zangerle, Olga Katsarou, Francois Dabis, Peter Reiss, John Gill, Kholoud Porter, Caroline Sabin, Andrew Riordan, Gerd Fätkenheuer, Félix Gutiérrez, Francois Raffi, Ole Kirk, Murielle Mary-Krause, Christoph Stephan, Patricia Garcia de Olalla, Jodie Guest, Hasina Samji, Antonella Castagna, Antonella d'Arminio Monforte, Adriane Skaletz-Rorowski, Jose Ramos, Giuseppe Lapadula, Cristina Mussini, Lluís Force, Laurence Meyer, Fiona Lampe, Faroudy Boufassa, Heiner C. Bucher, Stéphane De Wit, Greer A. Burkholder, Ramon Teira, Amy C. Justice, Tim R. Sterling, Heidi M. Crane, Jan Gerstoft, Jesper Grarup, Margaret May, Geneviève Chêne, Suzanne M. Ingle, Jonathan Sterne, and Niels Obel |
| Journal | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
| Volume | 58 |
| Issue | 9 |
| Pagination | 1312-21 |
| Date Published | 2014 May |
| ISSN | 1537-6591 |
| Keywords | Adult, Anti-HIV Agents, Cause of Death, CD4 Lymphocyte Count, Cohort Studies, Female, Heterosexuality, HIV Infections, Humans, Logistic Models, Male, Middle Aged, Risk Factors, Substance-Related Disorders, Viral Load |
| Abstract | Some human immunodeficiency virus (HIV)-infected individuals initiating combination antiretroviral therapy (cART) with low CD4 counts achieve viral suppression but not CD4 cell recovery. We aimed to identify (1) risk factors for failure to achieve CD4 count >200 cells/µL after 3 years of sustained viral suppression and (2) the association of the achieved CD4 count with subsequent mortality. |
| DOI | 10.1093/cid/ciu038 |
| Alternate Journal | Clin. Infect. Dis. |
